Spontaneous Regression Of A Conjunctival Malignant Melanoma
Miller, C. V., Cook, I. S., Jayaramachandran, R., & Tyers, A. G. (2014). spontaneous regression of a conjunctival malignant melanoma. Orbit (Amsterdam, Netherlands), 33(2), 139–141. https://doi.org/10.3109/01676830.2013.851708
View Original Source →Abstract
INTRODUCTION: Conjunctival malignant melanoma (MM) is a rare malignancy and accounts for 2% of all ocular malignancies. We describe what we believe to be the first reported case of complete spontaneous regression of a conjunctival malignant melanoma. METHODS: A 75-year-old female presented with a large, pigmented lesion in her left lower fornix. Histopathology revealed a mixed cell type MM. The tumour regressed spontaneously. Now, 6 years after she first presented, she remains well and there is no sign of recurrence or metastasis. CONCLUSION: Spontaneous regression is not always synonymous with complete cure from the underlying disease but may represent a temporary regression due to host protective mechanisms. In our patient regression and cure were complete.
Case Details
Disease Location
Left lower fornix conjivitual
Personal Characteristics
75 -year-old feacute myeloid leukemiae
Clinical Characteristics
Incitional biopsy nodular melanoma, neg met evaluationuiation.
Remission Characteristics
Regressed over several months, cr at 6 years followups
Treatment & Mechanisms
Proposed Remission Mechanisms
Immunologic reaction to biopsy
Clinical Treatment
Except biopsy