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Spontaneous Regression Of Neuroblastoma Detected By Mass Screening

Matsumura et al., 1991Neuroblastoma

Matsumura, M., Tsunoda, A., Nishi, T., Nishihira, H., & Sasaki, Y. (1991). spontaneous regression of neuroblastoma detected by mass screening. Lancet (London, England), 338(8764), 447–448. https://doi.org/10.1016/0140-6736(91)91072-3

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Case Details

Disease Location

Neuroblastoma - adrenal

Personal Characteristics

7- months-old boy diagnosed on primary biochemical screening

Clinical Characteristics

7 months boy diagnosed on urinary hva screening test at 6 months. Urine vma normal. Imaging confirmed a right suprarenal mass with no mets. Observation protocol followed with biochemistry and us q4weeks, CT MRI q3 months. Hva started declining at 12 months age. At 18 months, normal catecholamines and tumor was only 1/10th of original size but was resected after this (reason not given for resection).

Remission Characteristics

Hva started declining at 12 months age. At 18 months, normal catecholamines and tumor was only 1/10th of original size but was resected after this (reason not given for resection).

Treatment & Mechanisms

Proposed Remission Mechanisms

"""natural course"""

Clinical Treatment

Surgical resection