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Multicystic Dysplastic Kidneys; Spontaneous Regression Demonstrated With Ultrasound

Pedicelli et al., 1986Other/Unknown

Radiology 160(1): Oct 1986; 23-26

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Abstract

Two cases of unilateral multicystic kidney followed an atypical course, the non-communicating anechogenic images on ultrasound examination that projected into the renal region disappearing within several months and the infants’ condition appearing satisfactory at 2-year follow-up review. Analysis of the literature showed the increasing frequency of this outcome, but persistence of a multicystic kidney after the first year of life requires its surgical removal because of risk of degenerative changes.

Case Details

Personal Characteristics

Nine neonates

Clinical Characteristics

Spontaneous regression of a multicystic dysplastic kidney (mdck) was witnessed by means of repeated ultrasound (us) examinations

Remission Characteristics

Marked reduction in size or complete disappearance of the mcdk was observed on serial us examinations

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Three neonates underwent surgical exploration. No trace of a kidney, renal artery, or ureter was found in two. A small mcdk was removed in the third patient.

Additional Notes

Because malignant transformation of an MCDK is rare and because US provides a means of serial assessment, the authors believe a more conservative, nonsurgical approach is appropriate and recommend an observation time of 1 year before deciding on surgical intervention, unless other problems necessitate surgical removal of the MCDK.