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Variants Of Retroperitoneal Fibrosis

Harbrecht, P. J. 1967Other/Unknown

Annals of Surgery 165(3): March 1967; 338-401

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Abstract

The syndromes of idiopathic retroperitoneal fibrosis and mesenteric panniculitis are reviewed. Variants as reported in the literature are listed. Five patients with idiopathic fibrosis encountered at laparotomy are reported. Current concepts of the etiology and pathogenesis of idiopathic fibrosis are reviewed. The relationship of the idiopathic fibrotic processes to each other and to other fibrotic processes of the body is discussed.

Case Details

Personal Characteristics

A 48-year-old man

Clinical Characteristics

Large persistent intra-abdominal mass, symptoms of intermittent abdominal discomfort, cramping, bloating, easy fatigue, and weakness, yellowish tumor tissue which was very hard in some spots and soft in others, densely adherent to the vertebral bodies and large vessels, considered as malignant undifferentiated tumor, probably liposarcoma, extensive intra-abdominal adhesions, vague boundaries of the tumor, chronic fibrositis or sclerosing lipogranuloma

Remission Characteristics

Amazing regression of the mass and great improvement in symptoms

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Laparotomy, re-operation, lysis of adhesions, biopsy

Additional Notes

The tumor was considered inoperable and neither irradiation nor chemotherapy was advised. When last seen in August 1965 the mass was barely palpable and the patient was euphoric about his lack of symptoms.