Bronchial Reactivities To Acetylcholine And Ige Levels In Asthmatic Subjects After Long-term Remissions
Journal of Allergy and Clinical Immunology 54(1): July 1974; 32-40
View Original Source →Case Details
Clinical Characteristics
Serum ige concentrations, ige antibody titers to mite allergen, the number of blood eosinophils, the number of positive scratch tests, bronchial reactivity to acetylcholine
Remission Characteristics
Decreases in bronchial reactivity to acetylcholine after remission were observed in 7 of the 9 subjects
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Additional Notes
No correlation was obtained between bronchial reactivity and serum IgE. Of 7 asthmatics in remission having high serum IgE levels, 6 showed low bronchial responsiveness to acetylcholine, while the remaining one retained marked bronchial hyperreactivity. These results indicated that the atopic disposition of asthmatic subjects persisted but the bronchial reactivity to acetylcholine might decrease after long-term remission.