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Polyarteritis Nodosa: Chronic Renal Failure With Spontaneous Recovery

Szwed et al., 1983Other/Unknown

American Journal of the Medical Sciences 286(2): Sep-Oct 1983; 36-40

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Case Details

Personal Characteristics

A 57-year-old male

Clinical Characteristics

Acute oliguric renal failure, chronic renal failure, severe ischemic necrosis of his fingers, papular dermatitis of his lower extremities, edema, hypertension, reduced urine output, gross hematuria, tachypneic, blood pressure of 140/90, a third heart sound, dry gangrene of the right second and third fingers

Remission Characteristics

Recovered renal function with creatinine clearance of 30 ml/minute, ischemic lesions of his hands and feet resolved within 2 months of discharge, blood pressure was 140/80, regularly employed and asymptomatic on no drug therapy

Treatment & Mechanisms

Proposed Remission Mechanisms

Spontaneous remission

Clinical Treatment

Home hemodialysis

Additional Notes

The patient was not treated with drugs of any type for his illness. He represents a spontaneous remission from severe renal PAN and underscores the need for further evaluation of the current recommended drug therapy for this disease.