Congenital Self-healing Reticulohistiocytosis; Report Of A Patient With A Strikingly Large Tumor Mass
Pediatric Dermatology 6(1): Mar 1989; 28-32
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Personal Characteristics
Newborn male thai infant, birth weight was 2,850 grams, apgar scores were 9, 10, and 10 at 1, 2, and 5 minutes
Clinical Characteristics
Numerous brownish red nodules of various sizes, extremely large tumor mass on the right sole, spontaneous ulceration, no extracutaneous involvement, lesions involuted spontaneously within two to three months, some with scar formation, large numbers of mononucleated and multinucleated histiocytic cell infiltrations, 10% of which contained birbecks granules, areas of necrosis and calcification in the largest tumor
Remission Characteristics
All lesions involuted spontaneously within two to three months, some with scar formation. No recurrence was observed after follow-up for three years.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Additional Notes
The patient was born at full-term to a healthy primigravida, delivered by cesarean section because of fetal distress and meconium staining. No hepatosplenomegaly or lymph node enlargement was found. The patients general condition was satisfactory. Results of a complete blood cell count, urinalysis, and serum biochemical determination were normal. Examination of bone marrow aspirate was also normal. Bone survey demonstrated a shadow of a large soft tissue mass at the proximal part of the right foot with small, scattered, calcified spots throughout the mass. No lytic bone lesion was observed.