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Spontaneous Resolution Of Histiocytosis X; Report Of A Case

Meenan & Cahalane, 1967Other/Unknown

Archives of Dermatology 96: Nov 1967; 532-535

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Abstract

A case of histiocytosis X with spontaneous remission is described. The patient presented is an infant of six months, with cutaneous and bony lesions. No specific treatment was given, but the child was free of signs and symptoms two years later. The histological findings of eosinophils and fibrosis are probably of good prognostic import.

Case Details

Personal Characteristics

6-month-old female infant, firstborn child, normal weight and development for her age

Clinical Characteristics

Scaling follicular papular rash on the back and the occipital area of the scalp, slight swelling in the left parietal bone, hemoglobin, 10.5 gm/100 ml; hematocrit, 32%; white blood cells (wbc), 7,000/mm3 with a normal differential count; platelets, 246,000/mm3; erythrocyte sedimentation rate, 48 mm after one hour (westergren); urinalysis protein, + +, small amount of pus; urine culture yielded bacillus proteus

Remission Characteristics

Free of signs and symptoms two years later, skin eruption had completely disappeared leaving some slight depressed scars at the site of the lesions, bony lesions had completely cleared up

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Ampicillin for urinary infection

Non-Clinical Treatment

No specific treatment for histiocytosis x

Additional Notes

The histological findings of eosinophils and fibrosis are probably of good prognostic import