Cushing’s Syndrome And Pregnancy With Spontaneous Remission After Delivery

Abstract

To this date there have been 27 cases of Cushing’s syndrome and its relation to pregnancy published. This low frequency of association can be attributed to the fact that, generally speaking, suprarenal glucocorticoid hyperfunction is accompanied by problems with menstruation and/or infertility. Occasionally Cushing’s syndrome can undergo unexpected evolutive changes and various cases have been described of spontaneous remission in persons who weren’t pregnant, regardless of the cause of the syndrome. The period of gestation has been recognized as a factor that can modify the evolution of Cushing’s syndrome. In the majority of cases one observes an exacerbation or initiation of the clinical syndrome with remission following childbirth. But sometimes attenuation of the syndrome has been seen in the course of gestation. Following is a case of Cushing’s syndrome that appeared during pregnancy and disappeared after childbirth.