Spontaneous Remission Of Zollinger-ellison Syndrome
Archives of Internal Medicine 115: Jan 1965; 42-47
View Original Source →Abstract
A unique case of the Zollinger-Ellison syndrome is described with chronic diarrhea, multiple peptic ulcerations, gastric hypersecretion, and a mild malabsorptive state, undergoing spontaneous remission for 20 months after laparotomy and single lymph node biopsy of an invasive islet cell carcinoma of the head of the pancreas. The possible reasons for this result are discussed.
Case Details
Personal Characteristics
A 50-year-old welder
Clinical Characteristics
Chronic diarrhea, multiple peptic ulcerations, gastric hypersecretion, and a mild malabsorptive state
Remission Characteristics
Undergoing spontaneous remission for 20 months after laparotomy and single lymph node biopsy of an invasive islet cell carcinoma of the head of the pancreas
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Laparotomy and single lymph node biopsy
Additional Notes
The patient was treated in the hospital for two months with a bland diet, hourly antacids, anticholinergics, and sedation. He experienced moderate improvement in the pain and some decrease in the diarrhea but required analgesics periodically for relief of severe right upper quadrant pain.