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Spontaneous Remission From Primary Hypothyroidism

Yamamoto & Sakamoto, 1978Thyroid cancer

Annals of InternalMedicine 88(6): June 1978; 808-809

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Abstract

Primary hypothyroidism in adults has been thought to be an end result of the destructive process of chronic thyroiditis, for which life-long replacement therapy with desiccated thyroid or its equivalent has been an accepted method of treatment. In a recent issue of this journal, Amino et al. (Annals of Internal Medicine 87 (1977) 155-159) described their experience with transient hypothyroidism, which they observed in 14 postpartum women. The authors report the case of a 24-year-old woman who spontaneously recovered from hypothyroidism accompanied by goiter which was not associated with pregnancy. Twenty-one months after she was first evaluated she remained euthyroid without goiter. Serum thyroid hormones and TSH were normal. (Permission to reproduce case report denied by publisher.)

Case Details

Personal Characteristics

24-year-old woman

Clinical Characteristics

Hypothyroidism accompanied by goiter

Remission Characteristics

Spontaneously recovered from hypothyroidism, remained euthyroid without goiter

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Life-long replacement therapy with desiccated thyroid or its equivalent

Additional Notes

The case was not associated with pregnancy. Twenty-one months after she was first evaluated serum thyroid hormones and TSH were normal.