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Reversal Of Positive Serology For Human Immunodeficiency Virus (hiv); Observation Of Two Cases

Perrin et al., 1988Sarcoma

Schweizerische Medizinische Wochenschrift 118(45): Nov 12 1988; 1641-1644

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Abstract

Spontaneous healing has been described in classic Kaposi’s sarcoma (KS) and may represent up to 10% of these forms. It has also been observed in recipients of renal allografts, the sarcoma sometimes disappearing when immunosuppression is corrected. However, we know of only one report of spontaneously healing KS in the acquired immunodeficiency syndrome (AIDS). A case of spontaneously regressing KS in a 25-year-old homosexual man is reported.

Case Details

Personal Characteristics

The second observation is that of a single 34-year-old male in good health WHO reportedly engaged in bisexual behavior, and WHO spends several months a year in tropical regions. His medical history did not reveal other risk factors.

Clinical Characteristics

Physical examination and other laboratory data, including absolute number of CD4 lymphocytes/mm3, were within the normal range. Clinical examination of this patient was unremarkable.

Remission Characteristics

The serologic data of successive serum samples collected from these persons were first negative, then positive (including antibodies directed against gag and env gene products), and finally negative for presence of anti-HIV-i antibod-ies.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Additional Notes

At the beginning of his two latest trips, this subject presented to the Clinic of Dermatology for a check-up; he also asked to undergo a serologic test for HIV-1.