Spontaneous Regression of Primary Malignant Lymphoma of the Stomach in Two Nontreated Japanese

Case Details

Personal Characteristics

73-year-old japanese man

Clinical Characteristics

Protuberant tumor with a shallow ulcer and a smooth mucosal surface, positive for intracytoplasmic immunoglobulins, with a monoclonal pattern (IGG, lambda-type)

Remission Characteristics

Tumor had decreased in size, even though chemotherapy or radiotherapy had not been given. Tumor with the central ulceration had almost entirely disappeared

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Additional Notes

Although surgical resection was strongly recommended because a reappearance of the tumor was anticipated, the patient refused. Careful follow-up, including a gastroscopy with biopsy showing only erosive gastritis 8 months later, has been done thereafter. Recent barium studies of the upper gastrointestinal tract showed no sign of recurrent disease, 44 months after the tumor disappeared.