Spontaneous Remission In Diffuse Large Cell Lymphoma
Cancer 57(10): May 15 1986; 2042-2044
View Original Source →Abstract
One hundred twenty-six cases of cystic hygromas were seen in 10 years. More than two thirds of the cases were seen at birth or shortly thereafter. Inflammation occurred in 15.8%; hemorrhage into the hygroma in 12.6%. Radiotherapy has no place in management. Total excision is the only effective treatment. The natural history of lymphangiomas has not been studied extensively. Spontaneous regression is not given credence by most authors. We think that this notion should be re-examined. In our series, we have had two cases of spontaneous regression. Both patients were seen at the neonatal period; one had a fairly large cystic hygroma arising from the right supraclavicular fossa, the other had an even bigger one on the right side of the neck. Both tumors regressed spontaneously.
Case Details
Personal Characteristics
54-year-old woman
Clinical Characteristics
2-month history of a foreign body sensation in the throat, mass in the left vallecula, mobile tender lymph node in the left neck, 3 x 3 centimeter submucosal soft tissue mass arising from the left base of the tongue, 2 x 2 centimeter mass at the base of the tongue, 2 x 2 centimeter lymph node in the left cervical area
Remission Characteristics
Regression of the primary tumor mass, cervical lymph node regressed completely, physical exam was completely normal by late spring 1982
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Intravenous penicillin g for 5 days followed by oral cefazolin for 1 month, chemotherapy was recommended but withheld due to apparent regression of the primary tumor mass
Additional Notes
The patient remains well and without evidence of recurrent lymphoma 4 years after her original diagnosis