Spontaneous Regression Of Non-hodgkins Lymphoma; A Report Of Nine Cases
Cancer 46(9): Nov 1 1980; 2093-2099
View Original Source →Abstract
Complete spontaneous regression of high-grade malignant non-Hodgkin’s lymphoma is extremely unusual. In this report the authors describe a complete spontaneous remission after surgical excisional biopsy of a small noncleaved cell malignant lymphoma (non-Burkitt’s lymphoblastic lymphoma) of the tonsil in a 12-year-old boy. The diagnosis was confirmed by immunohistologic and immunoglobulin gene analysis. Similar studies were performed on the cervical lymph node excised 2 weeks later when spontaneous remission had occurred. The patient has remained in good health for over 3 years.
Case Details
Personal Characteristics
68-year-old woman
Clinical Characteristics
Asymptomatic right posterior cervical lymphadenopathy
Remission Characteristics
Three months later, it was noted that her peripheral lymphadenopathy had regressed. The left hilar mass on chest roentgenogram resolved and the abdominal lymphogram demonstrated marked reduction in the size of the involved lymph nodes.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Therapy was deferred
Additional Notes
She continues asymptomatic, without therapy, and without clinical evidence of disease two years after her first visit.