Congenital Neurofibromatosis; Multiple Subcutaneous Tumors With Spontaneous Regression In Twins

Abstract

Paragangliomas are rare neoplasms, most of which are benign, but malignant paragangliomas are occasionally encountered. The authors report a case of spontaneous remission of biopsy-proven metastatic pulmonary lesions from a malignant paraganglioma arising in the neck. We have no explanation for the regression of disease in our patient. We consider the case interesting because of the histologic confirmation of the metastatic lesions in the lung and because the regression began five months after chemotherapy had been stopped because of lack of response.