Congenital Neurofibromatosis; Multiple Subcutaneous Tumors With Spontaneous Regression In Twins
Acta Paediatrica Scandinavica 72(5): Sep 1983: 779-780
View Original Source →Abstract
Multiple subcutaneous tumors were found at birth in a pair of identical twins and the histological diagnosis was neurofibroma. The tumors disappeared within seven months. This disorder must be differentiated from congenital generalized fibromatosis, which usually shows a malignant course.
Case Details
Personal Characteristics
Male identical twin born in 1970, weighed 2,570 grams at birth, no cafe-au-lait spots, hyperactive behaviour
Clinical Characteristics
Multiple firm subcutaneous tumors, about 2 centimeters in diameter distributed all over his body at birth. One tumor eroding the left temporal bone
Remission Characteristics
The subcutaneous tumors started regressing spontaneously at the age of two months, and completely disappeared five months later
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Removal of one lesion and another tumor eroding the left temporal bone