Spontaneous Regression of Choroidal Melanoma Over Eight Years

Abstract

Spontaneous regression of hemangioma is well documented by Kingery, Margileth and Moss. The purpose of this presentation is to report a case in which the phenomenon is shown with extraordinary clarity.

Case Details

Personal Characteristics

A 66-year-old white man

Clinical Characteristics

Gradual, painless loss of vision in his right eye, brown choroidal tumor located superior to the optic disc and macula associated with serous subretinal fluid extending from the lesion into the center of the macula

Remission Characteristics

The tumor appeared slightly smaller. During the next 35 months, this tumor regression continued. The lesion became distinctly flatter and the basal margins receded centrally. A yellowish zone of chorioretinal atrophy developed around the residual lesion.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Barrier photocoagulation to wall of the subretinal fluid from the center of the macula. This treatment was performed using the argon blue green laser. The patient underwent uncomplicated bilateral extracapsular cataract extraction with implantation of a posterior chamber intraocular lens

Additional Notes

The authors observed clinical regression of an apparent primary choroidal melanoma in a 66-yearold man over an eight-year interval. This regression was documented photographically and ultrasonographically. The authors discuss the possible mechanisms responsible for this clinical course.