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Necrosis Of Malignant Melanoma Of The Choroid

Reese et al., 1970Melanoma

American Journal of Ophthalmology 69(1): Jan 1970; 91-104

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Abstract

In a histopathologic study of malignant choroidal melanoma, an attempt has been made to show that inflammation and necrosis may confuse the clinical picture, delaying the correct diagnosis. It is believed that these findings may represent an immunologic response which causes tumor regression. Several cases are cited describing spontaneous regression of lesions interpreted as malignant choroidal melanomas, in some instances to the point of cure.

Case Details

Clinical Characteristics

Inflammation and necrosis

Remission Characteristics

Spontaneous regression of lesions

Treatment & Mechanisms

Proposed Remission Mechanisms

Immunologic response

Additional Notes

The inflammation and necrosis may confuse the clinical picture, delaying the correct diagnosis. In some instances, the lesions interpreted as malignant choroidal melanomas regressed to the point of cure.