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Spontaneous Regression Of Bilateral Retinoblastoma

Sanborn et al., 1982Retinoblastoma

British Journal of Ophthalmology 66(11): 1982; 685-690

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Abstract

A 24-year-old black man was found to have bilateral, spontaneously regressed retinoblastoma that had previously been misdiagnosed as post-traumatic chorioretinal scarring. His son and halfbrother both had bilateral viable retinoblastoma. The ophthalmoscopic and fluorescein angiographic features of this patient’s fundus lesions included a calcified, whitish mass located centrally in one of the scars and a fine residual vascularity in another of the fundus lesions. The authors review the pertinent literature on spontaneous regression of retinoblastoma.

Case Details

Personal Characteristics

A 24-year-old black man

Clinical Characteristics

Bilateral, spontaneously regressed retinoblastoma that had previously been misdiagnosed as post-traumatic chorioretinal scarring. His son and halfbrother both had bilateral viable retinoblastoma. The ophthalmoscopic and fluorescein angiographic features of this patient’s fundus lesions included a calcified, whitish mass located centrally in one of the scars and a fine residual vascularity in another of the fundus lesions.

Remission Characteristics

Spontaneously regressed

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Additional Notes

The authors review the pertinent literature on spontaneous regression of retinoblastoma.