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Spontaneous Regression Of A Retinoblastoma

Brodwall, J. 1981Retinoblastoma

Acta Ophthalmologica 59(3): Jun 1981; 430-434

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Abstract

A case of bilateral retinoblastoma is reported. The eye most affected was removed and the diagnosis was histologically verified. In the remaining eye, which was left untreated, the tumour regressed spontaneously. The retinal characteristics have not changed throughout 44 years of observation.

Case Details

Personal Characteristics

A 3-year-old girl from an eye-healthy family

Clinical Characteristics

A yellow-green light reflex was observed in the blind left eye. A grey-white retinal tumour was found in the eye. In the right eye, a 3 to 4 diopter prominating tumour was observed. The left eye was removed and the diagnosis retinoblastoma was histologically verified. The other eye was left untreated.

Remission Characteristics

In the remaining eye, which was left untreated, the tumour regressed spontaneously. The retinal characteristics have not changed throughout 44 years of observation.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

The left eye was removed

Additional Notes

The patient was not reexamined before the age of 16 years. At the age of 47 she was control examined. She could still count fingers at 3 meters distance, and she read normal bookwriting with moderate hypermetropic correction (+ 2). She had given birth to two eye-healthy children.