Histology And Spontaneous Regression Of Retinoblastoma
Transactions of the Ophthalmological Society of the United Kingdom 94: 1974; 953-967
View Original Source →Abstract
A review of retinoblastoma is presented with example cases cited. It is of interest that all our spontaneously regressed tumours, bar one, are in males, though we also have one woman who retains her shrunken second eye which almost certainly contains an arrested tumour, and there is in addition an unproven female case with two shrunken eyes. Regressive changes certainly occur in shrunken eyes, but such histological evidence as we possess, taken in conjunction with the ophthalmoscopic appearance of these tumours, indicates that the process is one of spontaneous arrest rather than of regression.
Case Details
Personal Characteristics
All our spontaneously regressed tumours, bar one, are in males, though we also have one woman WHO retains her shrunken second eye which almost certainly contains an arrested tumour, and there is in addition an unproven female case with two shrunken eyes
Clinical Characteristics
Regressive changes certainly occur in shrunken eyes
Remission Characteristics
Spontaneous arrest rather than of regression
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Additional Notes
It is of interest that all our spontaneously regressed tumours, bar one, are in males, though we also have one woman who retains her shrunken second eye which almost certainly contains an arrested tumour, and there is in addition an unproven female case with two shrunken eyes. Regressive changes certainly occur in shrunken eyes, but such histological evidence as we possess, taken in conjunction with the ophthalmoscopic appearance of these tumours, indicates that the process is one of spontaneous arrest rather than of regression.