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Disappearance Of Metastases Following Nephrectomy For Carcinoma

Buehler et al., 1960Kidney cancer

Oklahoma State Medical Association. Journal 53(10): Oct 1960; 674-677

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Abstract

The thirteenth case of spontaneous regression of pulmonary metastases from a hypernephroma after simple nephrectomy is reported. The propensity for this to occur in men is observed, as is the appearance of other metastases while the lung lesions disappear. Some concepts are considered in relation to theories of action.

Case Details

Personal Characteristics

59-year-old white female, obese, appeared chronically ill

Clinical Characteristics

Severe pain in the left lower quadrant of the abdomen, chills, nausea, vomiting, cloudy urine, hypertension, old myocardial infarction, tenderness in the left upper quadrant of the abdomen and the left costovertebral angle, hydronephrotic left kidney, pulmonary metastases

Remission Characteristics

Regression of the previously described pulmonary lesions

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Left nephrectomy

Additional Notes

The patient has gained weight and is doing very well with no clinical or x-ray evidence of metastases 22 months post nephrectomy