Spontaneous Regression Of A Carcinoid Tumor Following Pregnancy.
Sewpaul, A., Bargiela, D., James, A., Johnson, S. J., & French, J. J. (2014). spontaneous Regression of a Carcinoid Tumor following Pregnancy. Case reports in endocrinology, 2014, 481823. https://doi.org/10.1155/2014/481823
View Original Source →Abstract
We present a case of spontaneous regression of a neuroendocrine tumor following pregnancy in the absence of chemotherapy, radiotherapy, or alternative medicine (including herbal medicine). The diagnosis of a nonsecretory carcinoid tumor was confirmed using CT imaging, octreotide scan, and histology. Furthermore, serial imaging has demonstrated spontaneous regression of the carcinoid suggesting that pregnancy did not worsen the course of the disease but instead may have contributed to tumour regression. We discuss mechanisms underlying tumour regression and the possible effect of pregnancy on these processes.
Case Details
Disease Location
Pelvic - right uterosacral region
Personal Characteristics
35-year-old female, undergoing inferightility evaluation
Clinical Characteristics
Woman diagnosed with tumor while undergoing workup for secondary inferightility, laparoscopic biopsy confirmed histology. Before any treatment could be started, she was pregnant. All treatment postponed with plans to resume after delivery. 3 months post partum (c-section), follow up octerotide scan confirms origin from distal ileum. 5 months post partum, CT scan repeated and no lesion/mass in the pelvis. Laparoscopy, colonoscopy with biopsy confirmed no tumor. Continued surveillance x 9 years (comprising of q2years mris) confirm remission.
Remission Characteristics
Found to have sr 5 moths post partum and remains in remission for 9 years of follow up.