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Spontaneous Regression Of The Metastasis Of Renal Carcinoma

Gutierrez et al., 1980Kidney cancer

Revista Clinica Espanola 158(3-4): Aug 15-31 1980; 163-166

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Abstract

The rare phenomenon of spontaneous regression of metastatic carcinoma is reported most commonly in association with renal adenocarcinoma. In 61 of the 68 reported cases the lungs have been the site of metastatic disease, and in only six of these cases had regression been reported before treatment. We report a further such case, and discuss the associated reversible hepatic dysfunction.

Case Details

Personal Characteristics

72-year-old woman, t.t.g., general symptoms of discomfort, anorexia, asthenia and loss of weight, ucl and diabetes, a large decubitis ulcer of 6 centimeters in diameter is in the sacral region

Clinical Characteristics

Multiple metastases of the lung, renal carcinoma diagnosed histologically, thyroid: cannot palpate the left lobe, the right lobe palpates much enlarged and consistently multinodular, a terminal mass superior to the left kidney, not homogeneous after the injection of the assay which suggested a vascularized tumor with necrotic areas

Remission Characteristics

Notable decrease of the large pulmonary metastasis, most of the pulmonary metastases were diminished in size and others had disappeared

Treatment & Mechanisms

Proposed Remission Mechanisms

Spontaneous reversion

Clinical Treatment

Chemotherapy was planned but not performed due to patient's decreasing stress

Additional Notes

The kidney in this case was not removed, the metastases disappeared without surgery or treatment of the primary tumor