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Spontaneous Regression Of Metastatic Renal Carcinoma

Kirk, D. 1987Kidney cancer

British Journal of Surgery 74(1): Jan 1987; 1-2

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Abstract

A case is described of apparent spontaneous regression of widespread pulmonary metastases from carcinoma of the kidney, in a man aged 61. Similar cases have previously been reported but, with one exception, have always followed nephrectomy. In the case described here, nephrectomy was not performed nor was any specific therapy given which might have caused regression of the metastases.

Case Details

Clinical Characteristics

The patient is alive and well over two and a half years after the diagnosis of pulmonary metastases from a renal tumour removed six months earlier.

Remission Characteristics

Spontaneous regression

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Removal of renal tumour

Additional Notes

The author raises several questions about the phenomenon of spontaneous regression of tumours. Prolonged survival can also occur in patients in whom the primary tumour is not removed. Idiopathic regression perhaps represents one further stage towards this end of the spectrum, a spectrum which unfortunately has at its other end the patient who dies within months of the removal of an apparently localized tumour.