Spontaneous Regression Of Hypernephromas

Abstract

A lesion with a papillomatous surface and composed of a center area of loose connective tissue surrounded by a capsular zone of denser connective tissue has been observed in the surface of the kidney in 26 cases. In 10 of the cases there were plainly evident remains of hypernephroma in the center area and in 7 cases there were groups of cells that resembled hypernephroma cells but could not be diagnosed as such with perfect certainty. In 9 cases displaying the same morphologic appearances no tumorous tissue was demonstrated. The material hitherto studied is too small to permit correct judgment as to the causal genesis. A slight tendency towards a higher incidence of these regressive hypernephromas among patients with tuberculosis was distinguishable. Attention is drawn to a few cases where a connection with endocrine disturbances was thought possible.