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Neuroblastoma; An Evaluation Of Its Natural History And The Effects Of Therapy, With Particular Reference To Treatment By Massive Doses Of Vitamin B12

Bodian, M. 1963Neuroblastoma

Archives of Diseases in Childhood 38: 1963; 606-619

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Case Details

Personal Characteristics

Female, born august 18, 1958. Enlarged abdomen noticed at 5 months

Clinical Characteristics

At 7 months she was admitted to local hospital, and referred here at 8 months, where gross liver enlargement was found with slightly nodular firm surface.

Remission Characteristics

After four months some regression of liver was noticed, and this improvement continued progressively. One year after onset of treatment there was only slight liver enlargement and consistency felt fairly normal. After two and a half years liver was considered to be of normal size and consistency.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Vitamin b12, 1 milligram, was instituted as sole form of therapy, and was given daily for first three months and on alternate days for remainder of three years.