Neuroblastoma; An Evaluation Of Its Natural History And The Effects Of Therapy, With Particular Reference To Treatment By Massive Doses Of Vitamin B12
Archives of Diseases in Childhood 38: 1963; 606-619
View Original Source →Case Details
Personal Characteristics
Female, born august 1, 1955, admitted here when 3 hours old
Clinical Characteristics
Huge nodular abdominal mass on right side extending from costal margin to inguinal ligament, and across to left flank, fixed and apparently arising from loin and indistinguishable from liver. Mass was palpable per rectum.
Remission Characteristics
After transient increase in size of abdomen, mass was decreasing by october 1955, and by february 1956 liver edge was barely palpable, and intravenous pyelogram was normal, without calcification in suprarenal regions. She had made uninterrupted progress, and is perfectly well without evidence of recurrence of tumour at 7 1/2 years.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Vitamin b12 1 milligram intramuscular, on alternate days was commenced, and continued for two and a half years as sole form of treatment.