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Neuroblastoma; An Evaluation Of Its Natural History And The Effects Of Therapy, With Particular Reference To Treatment By Massive Doses Of Vitamin B12

Bodian, M. 1963Neuroblastoma

Archives of Diseases in Childhood 38: 1963; 606-619

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Case Details

Personal Characteristics

Female, presented at 4 months

Clinical Characteristics

Weakness of both lower limbs, especially of left. Double sphincter weakness was suspected. Radiograph showed round, calcified paravertebral mass to left of upper lumbar spine.

Remission Characteristics

Vitamin b12 was continued and she progressed very well. In june 1957, however, she contracted bulbar form of poliomyelitis, nearly at the end of a two years’ course of vitamin b12. She succumbed within 30 hours of admission to hospital.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Vitamin b12 (1 milligram intramuscular on alternate days)

Additional Notes

Admitted to Beilinson Hospital, Israel