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The Treatment Of Neuroblastoma With Vitamin B12

Bodian, M. 1957Neuroblastoma

British Empire Cancer Campaign 35(2): 1957; 227-230

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Case Details

Personal Characteristics

Fifteen patients

Clinical Characteristics

Tumour regression, intercurrent infection (poliomyelitis)

Remission Characteristics

Fifteen patients had shown evidence of tumour regression, and ten were alive in remission at intervals from 7 months to 6 years from the commencement of treatment. One further child had succumbed to an intercurrent infection (poliomyelitis) and was then found to be free from tumour at autopsy. Regression in the remaining four children was of a temporary nature.

Treatment & Mechanisms

Clinical Treatment

Massive vitamin b12 therapy

Additional Notes

An annual survey of an investigation into the response of neuroblastoma to massive Vitamin B12 therapy has been provided in the Annual Reports from 1953 to 1956 inclusive. In the last issue the entire series was reviewed covering twenty-eight children where treatment was commenced between January 1951 and June 1956. Up to June 1957 treatment has been extended to include a further eight patients with neuroblastoma. Case summaries of Cases 31-38 are included.