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The Treatment Of Neuroblastoma With Vitamin B12

Bodian, M. 1956Neuroblastoma

British Empire Cancer Campaign 34: 1956; 213-216

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Case Details

Disease Location

Pelvic, abdominal

Personal Characteristics

A male infant admitted at 3 weeks of age

Clinical Characteristics

Flaccid paralysis of legs and an abdominal swelling, both apparent from birth

Remission Characteristics

After vitamin b12 therapy for 7 months the child continues to make good progress, though the paralysis is unrelieved

Treatment & Mechanisms

Proposed Remission Mechanisms

Vitamin b12 therapy might enhance the maturation of the neoplastic cells and bring about the conversion of the growth to a benign ganglioneuroma

Clinical Treatment

Vitamin b12 therapy, surgery and radiotherapy

Additional Notes

During the course of treatment, a remarkable regression of the massive pelvic tumour occurred, leading eventually to its complete disappearance