A searchable database of
medically documented cases

About the Project

I Simpatoblastomi

Antoniazzi, B. 1954Neuroblastoma

Tumori 40: 1954; 667-676

View Original Source →

Abstract

The histo-anatomical and clinico-radiological characteristics of sympathoblastomas are shortly reviewed and some particular possibilities of evolution are pointed out. Two of author's own cases illustrating peculiar clinical aspects and evolution of the disease are presented.

Case Details

Personal Characteristics

Two-year-old girl

Clinical Characteristics

Swelling on the right side of her head, lymphoglandular covered by unbroken skin with a hard consistency, roundish, intensely opaque and homogeneous formation with a well-defined profile, areas of necrosis and hemorrhage

Remission Characteristics

Lymphoglandular formation seated laterally on the head had completely disappeared, endothoracic tumor was greatly reduced, sickle-shaped calcification within the endothoracic swelling

Treatment & Mechanisms

Proposed Remission Mechanisms

Areas of necrosis and hemorrhaging which extended progressively toward the center of the tumor

Clinical Treatment

Biopsy of a lymph gland on the right side of the head

Additional Notes

The histological examination stated that the newly formed tissue has almost completely replaced the glandular lymphatic tissue. It is made up of diamond-shaped formations with lymphoblast and histiocyte-type cells whose cytoplasmic extensions collect at the center of the formations or get lost in a fine reticular woof that constitutes a common base to the whole tumor and that corresponds to fine amyelinic fibers. The histological diagnosis was sympathoblastoma. The report of a calcification within the context of the endothoracical tumoral mass, which was also reduced in volume, confirms this evolution.