Multiple Diffuse Hemangiomatosis; Case Report And Review Of The Literature
Zeitschrift für Kinderheilkunde (European Journal of Pediatrics) 117(2): 1974; 115-119
View Original Source →Abstract
Spontaneous regression is the natural history for congenital hemangiomas (strawberry nevi). Treatment is not indicated for most patients until the natural improvement has reached the maximum, since conventional methods of treatment may result in greater deformity. The best treatment for most of these patients is zealous neglect, although this may be most difficult. A case report is presented which illustrates spontaneous regression.
Case Details
Personal Characteristics
Newborn, first child of healthy parents, mother’s age was 27 years, father’s 32 years, no consanguinity, family history negative for congenital malformations, hemangiomata or congenital anomalies of the blood vessels
Clinical Characteristics
Fulminant outburst of cutaneous lesions during the first weeks of life, large number of hemangiomata all over the body, especially numerous on the chest and the abdomen, lesions bright red and became black on pressure, liver enlarged 4 centimeters below the costal margin, routine biochemical screening normal, platelet count 280,000/ mm3, urine analysis normal, skeletal survey revealed no hemangiomata in the bones, scintillation scintigraphy of the liver and the brain normal, biopsy of a skin lesion showed a typical capillary hemangioma
Remission Characteristics
Spontaneous regression began after the age of 6 months, striking involution of some lesions after 9 months, about 50% of the lesions were in complete regression at the age of 18 months, only 10% of the original lesions do not yet show any sign of involution
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Additional Notes
The child is doing well, and weight (11.2 kilograms) and height (83 centimeters) are in the 75th percentile for her age