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Multicentric Bowen’s Disease Of The Genitalia Spontaneous Regression Of Lesions

Berger & Hori, 1978Vulvar/vaginal cancer

Archives of Dermatology 114(11): Nov 1978; 1698-1699

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Abstract

J. L., a girl aged 4 years, had at birth a vascular nevus of the interscapular region which was soft, slightly raised and scarlet, apparently a typical strawberry mark. When the child was seen at the age of 18 months, the lesion measured 15 by 21 millimeters and was slightly raised. The surface had whitened somewhat but was studded with deep red points. In the belief that the type of nevus known as the strawberry mark almost invariably disappears spontaneously, no treatment was advised. Today the area is flat; a few red dots and a red line about the border are still visible. The case is presented for opinion as to the frequency of spontaneous disappearance of such lesions.

Case Details

Personal Characteristics

25-year-old woman, gravida 2, para 2

Clinical Characteristics

Vulvar lesions, brown to brown-black verrucose nodules, epidermal hyperplasia, parakeratosis, disorganization of epidermal cells, numerous mitotic figures, individual cell keratinization, lymphocytic infiltrates in the upper dermis, deformity of the nucleoli, indented nuclei, and nuclear bodies

Remission Characteristics

Lesions regressed within a threeweek period following her initial visit to our clinic, brown macules were all that remained of the original lesions, histologic examination of one of these macules showed no mitotic figures nor atypism of epidermal cells

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

No treatment was administered

Additional Notes

The patient has remained free of Bowen’s disease for the past two years