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Spontaneous Regression Of Intestinal Malignant Melanoma From An Occult Primary Site

Sroujieh, A. S. 1988Melanoma

Cancer 62(6): Sep 15 1988; 1247-1250

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Abstract

A case is reported in which recurring epithelial cancer disappeared after an attack of erysipelas. The case is reported without special comments, since Dr. Coley has written on this subject in considerable detail. The author is aware that a single case from the practice of a surgeon is but of little value, isolated and alone, but it is hoped that it will stimulate others to add their experience and observations.

Case Details

Personal Characteristics

55-year-old male

Clinical Characteristics

Melena, intussusception, dizziness, generalized weakness, subcutaneous mass in the right side of the neck, deep mass in the right suboccipital region, multiple black intramural ileal lesions, and mesenteric and paraaortic lymph node metastases

Remission Characteristics

Alive 8 years after diagnosis without evidence of malignancy

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Palliative and incomplete resection of an involved ileal segment, total excision of the subcutaneous mass in the neck, partial excision of the deep mass in the right suboccipital region

Additional Notes

The patient did not receive chemotherapy, radiotherapy, or immunotherapy. The case represents spontaneous regression of malignant melanoma of the small intestine that is considered either a primary intestinal tumor or a metastatic tumor from an occult regressed primary.