Complete Regression Of Primary Cutaneous Malignant Melanoma Associated With Distant Lymph Node Metastasis: A Teaching Case Mimicking Blue Nevus
Yamada, S., Nawata, A., Yoshioka, M., Hiraki, T., Higashi, M., Hatanaka, K., & Tanimoto, A. (2016). Complete regression of primary cutaneous malignant melanoma associated with distant lymph node metastasis: a teaching case mimicking blue nevus. BMC research notes, 9, 366. https://doi.org/10.1186/s13104-016-2174-4
View Original Source →Abstract
Careful, not only general/cutaneous but histopathological, examinations should be necessary and adjunctive aids for reaching the correct diagnosis of complete regression of cutaneous MM.
Case Details
Disease Location
Right sole foot
Personal Characteristics
65 yho male
Clinical Characteristics
Gradually growing and verrucous hypopigmented macule measuring up to 20 mm in the right sole. In parallel, the patient had a rapidly growing black-pigmented mass lesion at the right inguen. Mallignant melanoma with inguinal lymph nodes was suspected. Immunohistochemical studies of the lesion in the sole showed highly atypical mm cells. Microspcoy showed the absence of residual foci of the mms
Remission Characteristics
Primary regression without treatment, inguinal metastases were well controlled with systemic therapy.
Treatment & Mechanisms
Proposed Remission Mechanisms
None offered
Clinical Treatment
Biopsy 2 years post-operative treatment of chemotherapy, including dacarbazine, nimustine, cisplatin, tamoxifen, (dac-tam) and interferon-β, recurrence of small