The Spontaneous Cure of Massive Fibrosarcoma | Spontaneous Remission Database

Abstract

A case of complete resolution of a massive congenital fibrosarcoma of the head and face is presented. No clue as to the reasons for such resolution was found. The unpredictable course of these poorly classified lesions is emphasized and should be kept in mind when a decision regarding therapy is made.

Case Details

Personal Characteristics

A female infant was born spontaneously after full term normal gestation. At birth the infant was lusty and vigorous

Clinical Characteristics

Presented a massive tumor involving the left side of the head, face and neck. The neoplasm extended from the parietal region of the skull downward almost to the shoulder, anteriorly to the midcheek and posteriorly to the occiput. The skin overlying the mass was integrately fixed and showed many dilated veins on the surface. The consistency was almost homogenous, of firm rubbery quality. There was no mobility in any portion and the deep component was firmly fixed to the deep structures of the neck and to the skull. The auditory canal passed directly through the mass and was almost three times normal length because of the tumor thickness. The canal passage was collapsed by the encroachment of the mass.

Remission Characteristics

Two weeks after surgery, when the infant was 7 weeks old, the fixation of the skin overlying the tumor appeared to lessen and the tumor was softer. Within 4 weeks the size diminished and definite regression was visible. By 8 weeks, the mass reduced to one-half the original size and the overlying skin was normally movable. The mass disappeared at age 20 weeks, only 17 weeks after it had reached its maximum size. The child has been seen at frequent intervals and there has been no recurrence. The course of resolution was dramatic and complete.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

An incisional biopsy was performed at age 10 days at another hospital. Surgical exploration was carried out through a long, preauricular incision extending from the temple down around the ear lobule and over the mastoid region. Three sizable segments of the tumor were excised for microscopic study.

Additional Notes

The patient has been carefully followed for over 3 years without any suggestion of return growth of the tumor.