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A Case Of Spontaneous Regression Of An Untreated Bronchiogenic Carcinoma

Blades & Mccorkle, 1954Lung cancer

Journal of Thoracic and Cardiovascular Surgery 27: 1954; 415-419

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Abstract

No explanation has been found for the regression of this lung cancer. The postoperative temperature elevations were not high and cannot be regarded as significant. Drugs used by the patient are not considered important and, as far as it is known, have no carcinolytic properties. This case represents the only known instance of spontaneous regression of a bronchiogenic carcinoma. Despite evidence of metastasis to the skull, the patient remains in good health more than five years after the original diagnosis of bronchiogenic carcinoma.

Case Details

Personal Characteristics

A 59-year-old white man, smoker, history of liberal alcoholic intake, history of chronic bronchitis, exposure to noxious fumes due to occupation as a linotype operator

Clinical Characteristics

Chronic cough, malaise, increasing dyspnea, eighteen-pound weight loss, decreased breath sounds over both lung bases, opacity in the right lung field, leukocytosis, moderate anemia, carcinoma of the lung with involvement of the right hilum and invasion of the mediastinum, bone metastases

Remission Characteristics

Postoperative roentgenograms of the chest revealed progressive clearing of the pulmonary lesion in the right lung, particularly apparent about six months after the exploratory thoracotomy

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Right thoracotomy, biopsy of the mass, 300,000 units of penicillin daily for five days

Non-Clinical Treatment

Two halibut liver oil capsules daily, four vegetable compound tablets daily, an occasional barbiturate for sleep, and vitamin b1 tablets

Additional Notes

Despite evidence of metastasis to the skull, the patient remains in good health more than five years after the original diagnosis of bronchiogenic carcinoma