Spontaneous Regression of Mesenchymal Hamartoma: Observations Using Ultrasound

Case Details

Personal Characteristics

3-week-old male infant, normal and full-term at delivery, cyanosis on feeding, lower limb edema, cardiac murmur

Clinical Characteristics

Hard, irregular, mobile mass in the upper abdomen, raised alphafetoprotein (>450 miu/ml), raised gammaglutamyl transpeptidase (408 iu/l), right upper quadrant mass, abnormal area 8 x 5 x 7 centimeters in the midzone of the liver and extending into both lobes, vascular tumor extending into both lobes of the liver and involving the porta hepatis, mesenchymal hamartoma consisting of numerous cystic spaces, patchy calcification

Remission Characteristics

Mass decreased in size, measured 4 centimeters in diameter, echogenic area with associated acoustic shadowing, calcification confirmed by abdominal x-ray, mass slowly decreased in size over 2.5 years, only a transverse area of high echogenicity in the anterior and midzone of the liver remains

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Diuretic therapy and fluid restriction, laparotomy, wedge biopsy

Additional Notes

The tumor was considered unresectable