Regression Of A Localized Gastric Amyloid Mass In A Patient Treated For Multiple Myeloma.
Bhagat, G., Naiyer, A. J., & Green, P. H. (2009). Regression of a localized gastric amyloid mass in a patient treated for multiple myeloma. Gastrointestinal endoscopy, 69(4), 950–951. https://doi.org/10.1016/j.gie.2008.10.050
View Original Source →Case Details
Disease Location
Stomach
Personal Characteristics
82-year-old man with a 4-year history of multiple myeloma (k light chains), neuropathy, and macroglossia was admitted with vomiting and hematemesis.
Clinical Characteristics
Egd revealed gastric outlet obstruction with a copious amount of retained coffee-ground–stained fluid. After aspirating the fluid, a large circumferential antral mass considered most likely to be a gastric carcinoma
Remission Characteristics
Several days later, a repeat egd failed to reveal carcinoma, and biopsy specimens showed chronic inflammation, granulation tissue, and amyloid. A repeated egd performed 6 months after the initial endoscopy showed complete regression of the antral mass and random biopsy specimens revealed no evidence of amyloid deposition.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Zoledronic acid and lenalidomide, melphalan, dexamethasone (after remission)