Infantile Hemangioendothelioma Of The Liver; Report Of Three Cases
Pediatrics 19(4, part 1): Apr 1957; 596-605
View Original Source →Abstract
Three consecutive young female patients with unresected liver cell adenoma and a history of contraceptive use of several years’ duration were followed up over a period of 2-4.5 years after withdrawal of hormonal medication. One patient presented multiple adenomas and in another, the adenoma was associated with a Budd-Chiari syndrome due to bilateral thrombotic hepatic vein occlusion. Complete regression of the adenomas was documented in all 3 patients by ultrasonography, liver radionuclide scan, laparoscopy, or computerized tomography. It is concluded that, in selected cases, conservative management after withdrawal of hormonal contraception may be a valid alternative to surgical therapy.
Case Details
Personal Characteristics
6-month-old pale, irritable, anoretic negro female
Clinical Characteristics
Abdominal mass, protuberant abdomen with a hard, nodular mass filling the right upper quadrant, most of the left upper quadrant, and extending below the umbilicus on the right. A raised hemangioma, 0.6 x 0.6 centimeters, was noted on the right lateral aspect of the neck. No icterus. Large density in the right upper abdomen. Displacement downward and medially of the right renal pelvis, without distortion. Concentration of hemoglobin was 5.7 gm/100 ml.
Remission Characteristics
Definite regression in size of the liver. The liver has remained small.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Exploratory laparotomy
Additional Notes
The patient has remained in good health except for bronchial asthma. The anatomical diagnosis was infantile hemangioendothelioma of the liver.