A Case Of Spontaneous Regression Of Hepatocellular Carcinoma With Bone Metastasis
Cancer 56(3): Aug 1 1985; 667-671
View Original Source →Abstract
A 25-year follow-up is given on a patient who has undergone spontaneous remission of a massive liver tumor diagnosed as hepatoma at 5 1/2 months of age. His surprisingly benign clinical course prompted a review of the original biopsy material which has been reclassified as a vascular tumor, probably a variant of hemangioendothelioma.
Case Details
Personal Characteristics
78-year-old japanese man with chronic liver disease, no history of alcoholic ingestion
Clinical Characteristics
Hypervascular liver tumors, marked elevation of alphafetoprotein value, pathological fracture of the femur, gastrointestinal bleeding
Remission Characteristics
Tumors disappeared with normalization of the alphafetoprotein level, the radiolucent area around the fracture site of the femur became consolidated
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Operation for the fracture, transfusions of blood, open plating fixation of the fracture
Non-Clinical Treatment
Conservative treatments, medicines prescribed since june 1979: amoxicillin, hetacillin potassium, cefapirin sodium, doxycycline hydrochloride, spironolactone, furosemide, tranexamic acid, carbazochrome sodium sulfonate, pentazocine, antacids, anticholinergics, gefarnate, extract from hemolyzed blood of young calves (a medicine used for ulcer), polyenephosphatidyl choline, glutathione and lactulose
Additional Notes
Patient survives 62 months after the initial increase in alphafetoprotein level