Spontaneous Regression Of Metastatic Squamous Cell Lung Cancer.
Ariza-Prota, M., MARTínez, C., & Casan, P. (2018). spontaneous regression of metastatic squamous cell lung cancer. Clinical case reports, 6(6), 995–998. https://doi.org/10.1002/ccr3.1502
View Original Source →Abstract
Spontaneous regression (SR) of cancer is a rare but confirmed spectacular phenomenon, and it is even rarer in the context of advanced NSCLC. It is essential to understand this phenomenon in order to elucidate the nature of neoplastic disease and develop new treatment methods.
Case Details
Disease Location
Lung + multiple mets
Personal Characteristics
82-year-old man, 1 pack-a-day smoker for 45 years and had a history of type ii diabetes treated with medication
Clinical Characteristics
Pe showed palpable bilateral cervical lymph nodes and cutaneous nodules on his abdomen, arms, neck, and lip. CT scan revealed a round mass in the right lower lobe, multiple nodules in the chest wall (12x18 mm nodule in the right pectoral muscle and 6 mm nodule in the intercostal muscles between the sixth and seventh left ribs), and cervical necrotic lymph nodes. Cytology of the tumor on the left side of the cervical lymph node and CT-guided needle biopsy of the right lower lobe mass were performed, established the diagnosis of squamous lung cell carcinoma with metastases to the cervical lymph nodes.
Remission Characteristics
3 months after the diagnosis, chest radiography and CT scan showed that the primary tumor decreased in size and that metastatic cutaneous lesions (arms, neck, and lip), cervical lymph nodes and multiple nodules in the chest wall had spontaneously regressed
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Palliative thoracic radiotherapy (after partial remission)