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Spontaneous Resolution Of Multifocal Gastric Enterochromaffin-like Cell Carcinoid Tumours

Harvey, R. F. 8589Stomach cancer

Lancet 1(8589): Apr 9 1988; 821

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Abstract

A case is reported in which the patient was alive and well twelve years after a palliative resection for a malignant ulcerative adenocarcinoma of the left colon, Grade II. At operation, multiple liver metastases were found along with nodal involvement. When the patient was examined twelve years after operation, no evidence of carcinoma was found.

Case Details

Clinical Characteristics

Achlorhydria secondary to autoimmune atrophic gastritis

Remission Characteristics

Many of the tumours have spontaneously disappeared

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

Remained untreated but have been monitored endoscopically for some years

Additional Notes

The findings of these two patients suggest that in many multifocal ECL cell carcinoid tumours associated with achlorhydria and autoimmune atrophic gastritis may run a benign course which can end with the spontaneous regression of the tumors.