Nora's Lesion In A Child: A Case Of Complete Spontaneous Regression
Colangeli, M., Spinnato, P., Zarantonello, P., Bendandi, B., & Donati, D. M. (2021). Nora's Lesion in a Child: A Case of Complete Spontaneous Regression. Balkan medical journal, 38(1), 57–58. https://doi.org/10.4274/balkanmedj.galenos.2020.2020.7.224
View Original Source →Abstract
We describe a complete spontaneous regression of the Nora’s lesion of the first metatarsal in a 3-year-old child with hereditary sensory and autonomic neuropathy type IV (HSNA IV) with congenital insensitivity to pain and anhidrosis. The
Case Details
Disease Location
First metatarsal
Personal Characteristics
3-year-old. Hereditary sensory and autonomic neuropathy type IV with congenital insensitivity to pain and anhidrosis.
Clinical Characteristics
The patient presented with a non-tender mass in the dorsal region of the foot. The skin above the lesion was slightly warm without local bruising. Laboratory examinations revealed an elevated c-reactive protein (crp) level. X-ray scan and magnetic resonance imaging of the foot revealed a calcified mass adjacent to the cortical surface of the first metatarsal bone. Biopsy revealed a diagnosis of nora’s lesion. Intravenous antibiotic therapy (ceftriaxone, 50 mg/kg/day) was started to prevent infection.
Remission Characteristics
The x-ray imaging performed during the follow-up showed a progressive remission of the lesion with complete regression within 2 years
Treatment & Mechanisms
Proposed Remission Mechanisms
Nora’s lesion may be a reactive process
Clinical Treatment
Biopsy, antibiotic