A Rare Case Of Spontaneous Healing Of An Anterior Cruciate Ligament Tear
Baka, D. R., Thuo, E., Barshay, V., & Yun, D. S. (2025). A Rare Case of Spontaneous Healing of an Anterior Cruciate Ligament Tear. Cureus, 17(3), e80171. https://doi.org/10.7759/cureus.80171
View Original Source →Abstract
Anterior cruciate ligament (ACL) injuries are among the most common knee injuries in the United States. The ACL is an intra-articular ligament that resists anterior tibial translation and provides rotational stability. Most ACL injuries occur through non-contact mechanisms and are typically diagnosed based on history, physical examination, and confirmatory MRI. Treatment options include operative and non-operative management, with the latter focusing on restoring functional stability rather than expecting the ACL to heal spontaneously. In this case report, we present a 33-year-old female patient with a sedentary lifestyle who experienced a popping sensation and immediate swelling after twisting her knee while sitting down. She presented to the clinic one week later, reporting knee instability and a dull, aching pain rated 7/10. Physical examination revealed pain with passive knee extension and positive patellar compression, Clarke's inhibition, McMurray's, and Lachman's tests. MRI confirmed a complete ACL tear and a full-thickness cartilage defect in the medial facet of the patella. The patient opted for non-operative treatment, including a crossover knee brace and physical therapy. Over multiple follow-up visits, her range of motion and pain improved. Eleven months post-injury, a follow-up MRI ordered to evaluate a suspected reinjury unexpectedly revealed a completely intact ACL, indicating spontaneous healing. This case highlights a rare instance of spontaneous ACL healing in a sedentary adult who chose conservative management. Although non-operative therapy typically aims to restore function rather than facilitate ligament healing, emerging evidence suggests spontaneous ACL healing is possible, particularly in proximal femoral single-bundle tears. Further research is needed to establish standardized conservative treatment protocols that optimize outcomes and promote ACL regeneration.
Case Details
Disease Location
Knee (acl)
Personal Characteristics
33-year-old female
Clinical Characteristics
Presented one week after sustaining a non-traumatic right knee injury. The injury occurred while she was sitting and twisted her knee, hearing a popping sound, followed by swelling. At her initial clinic visit, she reported knee instability and episodes of the knee giving way. She described her pain as a dull ache, rated 7/10, which worsened with prolonged walking but improved with rest and analgesics. On physical examination, there was mild effusion (+1) and tenderness over both the medial and lateral joint lines. Her right knee range of motion (rom) was 0-100° with pain on passive extension. Special tests were positive for patella compression, clarke’s inhibition, mcmurray’s, and lachman’s tests an MRI performed 10 days post-injury confirmed a complete acl tear along with a full-thickness defect in the articular cartilage of the medial facet of the patella
Remission Characteristics
At her six-week follow-up, after two weeks of physical therapy, she reported no knee pain. Examination revealed resolution of knee effusion and joint line tenderness. Rom improved to 0-120° without pain on passive extension. Patella compression, clarke’s inhibition, and lachman’s tests remained positive, while mcmurray’s test was negative. MRI, performed 10.4 months post-injury, revealed decreased signal intensity compared to before, and an intact acl with evidence of a healed tear, as well as a full-thickness fissure in the articular cartilage of the medial patellar facet
Treatment & Mechanisms
Proposed Remission Mechanisms
Cross-over brace and attend physical therapy could have aided in spontaneous acl healing
Clinical Treatment
Cross-over brace, physical therapy
Non-Clinical Treatment
Work restrictions