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Spontaneous Regression Of An Isolated Retinal Astrocytic Hamartoma In A Newborn: A Case Report

Yang, B. 2023Other/Unknown

Yang, B., Li, D., & Xiao, J. (2023). Spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn: a case report. BMC ophthalmology, 23(1), 395. https://doi.org/10.1186/s12886-023-03135-5

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Abstract

BACKGROUND: To report the spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn. During the seven-month follow-up duration, fundus photography and fluorescein angiography examinations were performed. CASE PRESENTATION: An isolated retinal astrocytic hamartoma was detected in the nasal retina of the left eye of a 4-day-old male infant. At the time of initial presentation, we detected a solitary yellowish-white flat mass with an approximate size of 1.5 disc diameters in the nasal retina. Fluorescein angiography (FA) revealed a diffuse hyperfluorescence with slight fluorescence leakage. Seven months later, the fundus examination showed no lesion in the left eye, FA revealed mild tortuous vessels without leakage. CONCLUSIONS: In the present case, we established that the isolated retinal astrocytic hamartoma in this infant has underwent spontaneous regression. This case can point out that follow -up reexaminations are advisable for a solitary yellowish-white flat mass of the fundus in a newborn.

Case Details

Disease Location

Eye

Personal Characteristics

4-day-old male infant

Clinical Characteristics

Admitted due to dyspnea. A color fundus photograph of the left eye revealed a solitary yellowish-white flat mass with an approximate size of 1.5-disc diameters located in the nasal retina. He was diagnosed with retina astrocytic hamartoma (rah)

Remission Characteristics

Three months later, regression in the size of the retinal mass was observed. Seven months later, the fundus examination indicated no lesion in the left eye

Treatment & Mechanisms

Non-Clinical Treatment

None reported