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A Case Of Complete Spontaneous Regression Of Extensive Merkel Cell Carcinoma Involving The Orbit

Leung, V. C., Antonios, R., Désy, D., Rahal, A., & Boulos, P. R. (2021). A case of complete spontaneous regression of extensive Merkel cell carcinoma involving the orbit. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 56(1), e13–e15. https://doi.org/10.1016/j.jcjo.2020.06.022

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Abstract

exophytic solid and reddish mass with rapid growth over 4 months at the lower eyelid cheek junction. Histopathological studies revealed a diagnosis of Merkel cell carcinoma.

Case Details

Disease Location

Skin

Personal Characteristics

71-year-old woman

Clinical Characteristics

Presented with a 4-month history of a fast-growing, protruding mass on the left lower eyelid and cheek. Computed tomography revealed a 4 cm x 3 cm x 3 cm rounded isodense homogenous cutaneous/subcutaneous mass at the level of the left lower eyelid and inferior orbital rim with invasion into the intraorbital fat. An incisional biopsy was performed, and histology showed small blue cells with sparse cytoplasm and irregular hyperchromatic nuclei. Immunohistochemistry findings were diagnostic of mcc.

Remission Characteristics

At her first assessment 5 weeks after the biopsy, the patient remarked on progressive reduction in the size of the mass since the biopsy

Treatment & Mechanisms

Clinical Treatment

Biopsy