Spontaneous Regression Of Annular Basal Cell Carcinoma: A Case Report
Go, U., Miyata, K., Fujita, M., Ohide, T., & Mitsuishi, T. (2019). Spontaneous Regression of Annular Basal Cell Carcinoma: A Case Report. Case reports in dermatology, 11(2), 145–149. https://doi.org/10.1159/000500711
View Original Source →Abstract
We herein present a case of annular basal cell carcinoma (BCC) with spontaneous regression on the right temporal region of a 56-year-old Japanese male. Histopathological examination revealed that the central section had no tumor cells. The sweat glands, follicles, and other cutaneous appendages were also absent. This pattern of spontaneous regression is quite uncommon, and understanding the histopathology may be important for future approaches to BCC.
Case Details
Disease Location
Skin
Personal Characteristics
56-year-old japanese male
Clinical Characteristics
Presented with an annular nodule on the right temporal region. Clinical examination revealed normal skin color in the central section of the lesion, surrounded by dark black nodules, and it had a centrifugal pattern of spread. The tumor size was 42 mm × 28 mm in diameter. Skin biopsy from the nodules was performed, and basal cell carcinoma (BCC) was diagnosed histopathologically. The nodule was excised. Histopathological analysis of the tissue excised from the central section revealed no tumor nests. The cutaneous appendages, such as sebaceous glands and hair follicles, were also not found
Remission Characteristics
The nodule was excised. Histopathological analysis of the tissue excised from the central section revealed no tumor nests. The cutaneous appendages, such as sebaceous glands and hair follicles, were also not found. Immunohistochemical staining, and CD8+ cells and CD68+ cells infiltrated the tumor nests.
Treatment & Mechanisms
Proposed Remission Mechanisms
CD8+ and CD68+ cells might play a role in the spontaneous regression of BCC
Clinical Treatment
Biopsy excision